Sodium Bromide USP Grade Specifications:
NaBr --- 102.89
Sodium bromide.
Sodium bromide --- CAS 7647-15-6

Sodium Bromide contains not less than 98.0 percent and not more than 100.5 percent of NaBr, calculated on the dried basis. It contains no added substances.

Packaging and storage:Preserve in well-closed containers, and store at room tem perature.

Appearance of solution: clear and colorless.

Test solution: Dissolve 10.0 g in carbon dioxide-free water, and dilute with the same solvent to 100 mL.

Identification: A: A solution containing 4.0 mg of sodium bromide responds to the test for Bromide.
B: It responds to the test for Sodium.

Acidity or alkalinity: To 10 mL of the solution prepared for the test for Appearance of solution, add 0.1 mL of bromothymol blue: not more than 0.5 mL of 0.01 N hydrochloric acid or 0.01 N sodium hydroxide is required to change the color of this solution.

Loss on drying: Dry it at 100C to 105C for 3 hours: it loses not more than 3.0% of its weight.

Bromates: Starch-mercuric iodide solution: Triturate 1.0 g of soluble starch with 5 mL of water, and pour the mixture into 100 mL of boiling water containing 10 mg of mercuric iodide.

Procedure: To 10 mL of the solution prepared for the test for Appearance of solution add 1 mL of Starch–mercuric iodide solution, 0.1 mL of a 100 g per L solution of potassium iodide, and 0.25 mL of 0.5 M sulfuric acid. Allow to stand protected from light for 5 minutes. No blue or violet color develops.

Limit of chlorine: not more than 0.6%.

Iodides: To 5 mL of the solution prepared for the test for Appearance of solution add 0.15 mL of a 10.5 g per 100 mL ferric chloride solution, and 2 mL of dichloromethane. Shake, and allow to separate. The lower layer is colorless.

Sulfates: A 2.0-g portion shows no more sulfate than corresponds to 0.2 mL of 0.020 N sulfuric acid (0.01%).

Limit of iron: not more than 20 ppm.

Magnesium and alkaline-earth metals: To 200 mL of water add 0.1 g of hydroxylamine hydrochloride, 10 mL of pH 10.0 ammonia–ammonium chloride buffer (prepared by dissolving 5.4 g of ammonium chloride in 20 mL of water, adding 20 mL of ammonium hydroxide, and diluting to 100 mL), 1 mL of 0.1 M zinc sulfate, and about 0.2 g of eriochrome black T trituration. Heat to about 40C. Titrate this solution with 0.01 M edetate disodium until the violet color changes to deep blue. To this solution add 10.0 g of Sodium Bromide dissolved in 100 mL of water. If the color changes to violet, titrate the solution with 0.01 M edetate disodium to a deep blue endpoint. The volume of 0.01 M edetate disodium consumed in the second titration does not exceed 5.0 mL (0.02%, calculated as Ca).

Specifications of Sodium Bromide BP Ph Eur Grade
102.9 --- CAS 7647-15-6

DEFINITION
Content: 98.5 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, granular powder or small, colourless, transparent or opaque crystals, slightly hygroscopic.
Solubility: Freely soluble in water, soluble in ethanol (96 per cent).

IDENTIFICATION
A. It gives reaction (a) of bromides.
B. Solution S (see Tests) gives the reactions of sodium.

TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 10 mL of solution S add 0.1 mL of bromothymol blue solution. Not more than 0.5 mL of0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Bromates: To 10 mL of solution S add 1 mL of starch solution, 0.1 mL of a 100 g/L solution of potassium iodide and 0.25 mL of 0.5 M sulfuric acid and allow to stand protected from light for 5 min. No blue or violet colour develops.
Chlorides and sulfates: Limits: chlorides: maximum 0.6 per cent; sulfates: maximum 0.01 per cent.
Iodides: To 5 mL of solution S add 0.15 mL of ferric chloride solution and 2 mL of methylene chloride. Shake and allow to separate. The lower layer is colourless.
Iron: Maximum 20 ppm.
Magnesium and alkaline-earth metals: Maximum 200 ppm, calculated as Ca.
Loss on drying: Maximum 3.0 per cent, determined on 1.000 g by drying in an oven at 105C for 3 h.

Sodium Bromide Analytical Reagent Grade
NaBr
Formula Weight: 102.89
CAS Number: 7647-15-6

REQUIREMENTS
Assay (corrected): 99.0% NaBr
pH of a 5% solution: 5.0-8.8 at 25C

Insoluble matter: 0.005%
Bromate (BrO3): 0.001%
Chloride (Cl): 0.2%
Nitrogen compounds (as N): 5 ppm
Sulfate (SO4): 0.002%
Barium (Ba): 0.002%
Heavy metals (as Pb): 5 ppm
Iron (Fe): 5 ppm
Calcium (Ca): 0.002%
Magnesium (Mg): 0.001%
Potassium (K): 0.1%.