Potassium Acetate USP Grade Specifications:
C2H3KO2 --- 98.14
Acetic acid, potassium salt
Potassium acetate CAS 127-08-2

DEFINITION
Potassium Acetate contains NLT 99.0% and NMT 100.5% of C2H3KO2, calculated on the dried basis.

IDENTIFICATION
A. Identification Tests—General, Potassium.
B. Identification Tests—General, Acetate.

ASSAY
Procedure
Sample: 200 mg of Potassium Acetate, previously dried
Analysis: Dissolve the Sample in 25 mL of glacial acetic acid, add 2 drops of crystal violet and titrate with 0.1 N perchloric acid to a green endpoint. Perform a blank determination and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 9.814 mg of potassium acetate (C2H3KO2).
Acceptance criteria: 99.0% to 100.5% on the dried basis

Specifications of Potassium Acetate BP Ph Eur Grade
C2H3O2K -- 98.14 -- 127-08-2

DEFINITION
Potassium acetate contains not less than 99.0 per cent and not more than the equivalent of 101.0 per cent of C2H3KO2, calculated with reference to the dried substance.

CHARACTERS
A white, crystalline powder or colourless crystals, deliquescent, very soluble in water, freely soluble in alcohol.

IDENTIFICATION
A. It gives reaction of acetates.
B. It gives reaction of potassium.

TESTS
Solution S: Dissolve 10.0 g in distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: Dissolve 1.0 g in carbon dioxide-free water and dilute to 20 ml with the same solvent. The pH of the solution is 7.5 to 9.0.
Reducing substances: Dilute 10 ml of solution S to 100 ml with water. Add 5 ml of dilute sulphuric acid and 0.5 ml of a 0.32 g/l solution of potassium permanganate. Mix and boil gently for 5 min. The solution remains pink.
Chlorides: Dilute 2.5 ml of solution S to 15 ml with water. The solution complies with the limit test for chlorides (200 ppm).
Sulphates: Dilute 7.5 ml of solution S to 15 ml with distilled water. The solution complies with the limit test for sulphates (200 ppm).
Aluminium: If intended for use in the manufacture of peritoneal dialysis solutions, haemofiltration solutions or hem dialysis solutions, it complies with the test for aluminium. Dissolve 2.0 g in 50 ml of water and add 5 ml of acetate buffer solution pH 6.0. The solution complies with the limit test for aluminium (1 ppm). Use as a reference solution a mixture of 1 ml of aluminium standard solution (2 ppm Al), 5 ml of acetate buffer solution pH 6.0 R and 49 ml of water. To prepare the blank use a mixture of 5 ml of acetate buffer solution pH 6.0 R and 50 ml of water.
Iron: Dilute 5 ml of solution S to 10 ml with water. The solution complies with the limit test for iron (20 ppm).
Heavy metals: Dissolve 5.0 g in water and dilute to 20 ml with the same solvent. 12 ml of the solution complies with limit test A for heavy metals (4 ppm). Prepare the standard using lead standard solution (1 ppm Pb).
Sodium: Not more than 0.5 per cent of Na, determined by atomic emission
Loss on drying: Not more than 3.0 per cent, determined on 1.000 g by drying in an oven at 100C to 105C.

Potassium Acetate Analytical Reagent Grade Specifications
CH3COOK
Formula Weight. 98.14
CAS Number 127-08-2

REQUIREMENTS
Assay: 99.0% CH3COOK
pH of a 5% solution: 6.5-9.0 at 25C

MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Chloride (Cl): 0.003%
Phosphate (PO4): 0.001%
Sulfate (SO4): 0.002%
Heavy metals (as Pb): 5 ppm
Iron (Fe): 5 ppm
Calcium (Ca): 0.005%
Magnesium (Mg): 0.002%
Sodium (Na): 0.03%