Specifications of Butylated Hydroxyanisole USP NF Grade
C11H16O2 --- 180.24
Phenol, (1,1-dimethylethyl)-4-methoxy-.
tert-Butyl-4-methoxyphenol CAS 25013-16-5

Butylated Hydroxyanisole contains not less than 98.5 percent of C11H16O2.

Identification: To 5 mL of a 1 in 10,000 solution in 72% alcohol add 2 mL of sodium borate solution (1 in 50) and 1 mL of a 1 in 10,000 solution of 2,6-dichloroquinone-chlorimide in dehydrated alcohol, and mix: a blue color is produced.
Residue on ignition: not more than 0.01%, determined on a 10-g specimen.
Heavy metals: 0.001%.
Organic volatile impurities: meets the requirements.

BHA Butylated Hydroxyanisole FCC Food Grade
C11H16O2 Formula wt 180.25
INS: 320 CAS 25013-16-5

DESCRIPTION
BHA occurs as a white or slightly yellow, waxy solid. It is predominantly 3-tert-butyl-4-hydroxyanisole (3-BHA), with varying amounts of 2-tert-butyl-4-hydroxyanisole (2-BHA). It melts between 48C and 63C. It is freely soluble in alcohol and in propylene glycol, and insoluble in water.
Function: Antioxidant.

Specifications of Butylated Hydroxyanisole BP Ph Eur Grade
Butylhydroxyanisole Ph Eur
C11H16O2 --- 180.3 --- CAS 25013-16-5
Action and use: Antioxidant.

Specifications of Butylated Hydroxyanisole BP Ph Eur Grade
Butylhydroxyanisole Ph Eur
C11H16O2 --- 180.3 --- CAS 25013-16-5
Action and use: Antioxidant.

DEFINITION
Butylhydroxyanisole is 2-(1,1-dimethylethyl)-4-methoxyphenol containing not more than 10 per cent of 3-(1,1-dimethylethyl)-4-methoxyphenol.

CHARACTERS
A white, yellowish or slightly pinkish, crystalline powder, practically insoluble in water, very soluble in methylene chloride, freely soluble in alcohol and in fatty oils. It dissolves in dilute solutions of alkali hydroxides.

IDENTIFICATION
A. Examine the chromatograms obtained in the test for related substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
B. To 0.5 ml of solution S (see Tests) add 10 ml of aminopyrazolone solution and 1 ml of potassium ferricyanide solution. Mix and add 10 ml of methylene chloride. Shake vigorously. After separation, the organic layer is red.
C. Dissolve about 10 mg in 2 ml of alcohol. Add 1 ml of a 1 g/l solution of testosterone propionate in alcohol and 2 ml of dilute sodium hydroxide solution. Heat in a waterbath at 80C for 10 min and allow to cool. A red colour develops.

TESTS
Solution S: Dissolve 2.5 g in alcohol R and dilute to 25 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than intensity 5 of the range of reference solutions of the most appropriate.
Related substances: To pass the test --- (0.5 per cent).
Heavy metals: 1.0 g complies with limit test C for heavy metals (10 ppm). Prepare the standard using 1 ml of lead standard solution (10 ppm Pb).
Sulphated ash: Not more than 0.1 per cent, determined on 1.0 g.