Ammonium Chloride USP Grade Specifications
NH4Cl 53.49

Assay: Ammonium Chloride contains not less than 99.5 percent and not more than 100.5 percent of NH4Cl, calculated on the dried basis.
Identification: A solution (1 in 10) responds to the tests for Ammonium and for Chloride
pH: between 4.6 and 6.0, in a solution (1 in 20).
Loss on drying: Dry it over silica gel for 4 hours: it loses not more than 0.5% of its weight.
Residue on ignition: Add 1 mL of sulfuric acid to about 2 g, accurately weighed, and heat the mixture gently until volatilization is complete: the residue is white, and when ignited, not more than 0.1% of nonvolatile substance remains.
Limit of thiocyanate: Acidify 10 mL of a solution (1 in 10) with hydrochloric acid, and add a few drops of ferric chloride TS: no orange-red color is produced.
Heavy metals: 0.001%.

Ammonium Chloride BP Ph Eur Grade Specifications
NH4Cl

Ammonium Chloride BP Ph Eur Grade Specifications
NH4Cl

CHARACTERS
Appearance
White or almost white, crystalline powder or colorless crystals.
Solubility
Freely soluble in water.

IDENTIFICATION
A. It gives the reactions of chlorides.
B. 10 ml of solution gives the reaction of ammonium salts.

TESTS
Solution S: A 10% solution:
Appearance of solution: Solution is clear and colorless.
Acidity or alkalinity: To 10 ml of solution S add 0.05 ml of methyl red solution. Not more than 0.5 ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the color of the indicator.
Bromides and iodides: To 10 ml of solution S add 0.1 ml of dilute hydrochloric acid R and 0.05 ml of chloramine solution. After 1 min, add 2 ml of chloroform R and shake vigorously. The chloroform layer remains colorless.
Sulphates: Maximum 150 ppm.
Calcium: Maximum 200 ppm.
Iron: Maximum 20 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 1.0 per cent, determined on 1.00 g by drying in an oven at 105C for 2 h.
Sulphated ash: Maximum 0.1 per cent, determined on 2.0 g.

Ammonium Chloride Analytical Reagent
NH4Cl Formula Weight 53.49
CAS Number 12125-02-9

REQUIREMENTS
Assay: 99.5% minimum NH4Cl
pH of a 5% solution: 4.5 to 5.5 at 25C

MAXIMUM ALLOWABLE
Insoluble matter:0.005%
Residue after ignition: 0.01%
Calcium (Ca): 0.001%
Magnesium (Mg): 5 ppm
Heavy metals (as Pb): 5 ppm
Iron (Fe): 2 ppm
Phosphate (PO4): 2 ppm
Sulfate (SO4): 0.002%